In labs and health care facilities worldwide - HERE WE ARE

Thermo Fisher's clinical research business is a leading global contract research organization and world leader in serving science. We are passionate, deliberate, and driven by our mission – to enable our customers to make the world healthier, safer, and cleaner.

Within our Analytical Services team, we have a functional service provider solution, which is a unique partnership that allows our customers to leverage the experience of our staff, while allowing you, the employee, to gain direct experience working onsite at a pharmaceutical/ biopharmaceutical company, all while maintaining full-time benefits.

Essential Functions:

• Perform detailed structural characterization including protein primary sequence confirmation, sequence variant identification, qualitative and quantitative analysis of post-translational modifications (e.g. glycosylation and disulfide bonds) and charge variant analysis in support of Discovery, IND enabling studies, forced degradation and comparability studies.
• Collaborate with AD team and cross-functional teams to support protein engineering, process development, and formulation studies.
• Evaluate and implement new analytical approaches, automation, and software to improve the quality and efficiency of the characterization workflows and to solve problems encountered during drug development.
• Author technical reports, protocols and manuscripts for publication; present at internal and external conferences.
• Collaborate with Discovery small molecule team to conduct target characterization/mechanism studies.
• Conduct scheduled preventive maintenance and qualification of equipment (e.g., MS, HPLC, etc.) and software
• Ensure execution of work assignments by laboratory staff to meet cycle times
• Review peer's work

At PPD, part of Thermo Fisher Scientific we hire the best, develop ourselves and each other, and recognize the power of being one team. We offer continued career advancement opportunities, award winning training and benefits focused on the health and wellbeing of our employees.

To learn how PPD, part of Thermo Fisher Scientific can advance your career, apply now!

***This position requires long term eligibility to work in the US without sponsorship. Please note F-1 OPT Visas are not considered long term eligibility for this role.

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Education and Experience:

• Bachelor's degree, Master’s degree or PhD in analytical chemistry, biochemistry, molecular biology or equivalent and relevant formal academic / vocational qualification
• Previous industry experience that provides the knowledge, skills, and abilities to perform the job:
  • Associate Research Scientist: With a bachelor’s degree comparable to 6+ years, with a master’s degree comparable to 4+ years, with a PhD comparable to 2+ years.

In some cases, an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.

Knowledge, Skills and Abilities:

• Expertise in protein mass spectrometry including LC-MS intact protein analysis, peptide mapping, and PTM characterization.
• Expertise in protein charge variant analysis using cIEF instruments.
• Basic statistical knowledge is required.
• Experience with protein quantitation is preferred.
• Advanced knowledge of cell biology, cancer biology is preferred.
• Computer applications and proficiency
• Oral and written communications
• Data recording, interpretation, and management
• Ability to work in a collaborative work environment with a team.

Working Environment:

PPD, part of Thermo Fisher Scientific values the health and well being of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive. Below is listed the working environment/requirements for this role:

• Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
• Able to work upright and stationary and/or standing for typical working hours.
• Able to lift and move objects up to 25 pounds.
• Able to work in non-traditional work environments.
• Able to use and learn standard office equipment and technology with proficiency.
• May have exposure to potentially hazardous elements, including infectious agents, typically found in healthcare or laboratory environments.
• Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.
• As a condition of employment with PPD, in this role, you must have received your Covid-19 vaccine and you must disclose proof of your vaccination status upon employment.

Our 4i Values:

Integrity – Innovation – Intensity – Involvement

If you resonate with our 4i values above, and ultimately wish to accelerate the delivery of safe and effective therapeutics for some of the world’s most urgent health needs, submit your application – we’d love to hear from you!