Scientist - Antibody Engineering, Immunology Job at Adimab

Adimab Lebanon, NH 03766

Adimab is the leading provider of therapeutic antibody discovery and engineering technologies. This includes naïve discovery from synthetic libraries in yeast or B cells (mice and humans), antibody engineering and optimization, multi-specific antibody engineering, and a portfolio of proprietary CD3 antibodies licensed non-exclusively for bispecific applications. Adimab focuses solely on its partners and not on developing an internal product pipeline. Since 2009, Adimab has partnered with over 105 pharmaceutical and biotechnology companies, generating more than 475 therapeutic programs, over 60 clinical programs, and its first approved product. The Adimab technology has been transferred and implemented at Biogen, GSK, Lilly, Merck, Novo Nordisk, and Takeda. Funded discovery partners include leading pharmaceutical companies, such as Boehringer Ingelheim, Bristol Myers Squibb, Novartis, Regeneron, Sanofi, Takeda and others. Adimab has also partnered with many early-stage venture-backed companies, including Amagma, Dragonfly, iOmx, NextPoint, Pliant, Tizona, TRex Bio and others, as well as mid-size public biopharmaceutical companies such as Alector, Cullinan Oncology, Innovent, Jounce, Mersana, Scholar Rock, Surface Oncology, and others.

Adimab’s integrated antibody discovery and engineering platform provides unprecedented speed from antigen to purified, full-length human IgGs. Adimab offers fundamental advantages by delivering diverse panels of therapeutically relevant antibodies that meet the most demanding standards for affinity, epitope coverage, species cross-reactivity, and developability. Adimab enables its partners to rapidly expand their biologics pipelines through a broad spectrum of technology access arrangements.

Role

We are seeking an experienced Immunologist with experience in mammalian immunization and single B cell cloning to join our research team. The successful candidate will play a key role in developing novel methods and technologies for the discovery of antibody therapeutics. This individual will be expected to lead and/or support a range of projects related to antibody discovery and optimization, developability analysis, B cell cloning, library development, reagent design, immunization techniques, and commercial platform development.

Responsibilities

  • Initiate, execute, and interpret innovative research
  • Internal technology development; focus on mammalian immunization, library development, and B cell cloning technologies
  • Develop and implement new drug discovery technology
  • Read papers, contribute to company-wide scientific discussion, and bring new ideas to the table
  • Successfully collaborate with multiple teams and departments

Needed upon hire

  • Ph.D. or equivalent practical experience documented by relevant publications
  • A track record of designing experiments and bringing them to a publishable result; a thinker and a doer
  • Desire to meticulously execute bench work
  • Knowledge, experience, and interest in display technologies and antibody or protein engineering
  • Experience with handling mammalian immune cells, B cell cloning, murine or large mammal immunization, multicolor flow cytometry, and molecular biology techniques
  • Knowledge of basic B cell biology, immunization concepts, antibody responses, and protein engineering
  • Curiosity and passion for science demonstrated by reading scientific literature
  • Natural inclination to seek out the data source and engage directly with problems
  • Proficiency with cell culture preferred
  • Adaptable and productive in a fast-paced environment
  • Communicates effectively and openly with colleagues and supervisors

Come join us!

As a profitable privately-held biotech company, we take a long-term view on value creation and make substantial investments in technology development, research, and our people. We proudly promote meritocracy and reward employees who are productive, use their resources wisely, and make meaningful contributions to the team. We offer individually tailored compensation packages comprised of a competitive salary, meaningful equity, a 2:1 401(k) match, and comprehensive health care benefits.

Located in New Hampshire’s beautiful Upper Connecticut River Valley, we are minutes from Dartmouth College, the Geisel School of Medicine, the Thayer School of Engineering, the Tuck School of Business, and the Dartmouth Hitchcock Medical Center. We are fortunate to be situated in an area that is renowned for its premier skiing, hiking, kayaking, and biking.

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