Location: Remote in the United States

About our Company: Foresight Diagnostics is an early-stage, venture-backed molecular diagnostics company that is developing non-invasive cancer detection technologies to improve the lives of patients worldwide. Our portfolio of cell-free DNA based liquid biopsy tests are rooted in novel and proprietary methods developed at Stanford University. Our approach enables the earlier detection of smaller tumors, leading to more personalized and effective cancer treatment strategies for patients. We have deep expertise in molecular biology, bioinformatics, and Next Generation Sequencing (NGS), and maintain a dynamic, fast-paced work environment with significant opportunities for high-impact contribution and rapid professional growth. Foresight Diagnostics is headquartered in Aurora, Colorado.

About the Role: As a Bioinformatics Scientist, you will develop algorithms for cutting-edge detection of circulating tumor DNA. You will extract biological signals from complex molecular data, leveraging machine learning and statistics, to advance our understanding of cell-free DNA as a biomarker and translate this understanding into Foresight’s products for managing cancer care. You will work cross-functionally with wetlab scientists to design experiments and interpret results to advance new laboratory methods. Subject matter expertise in genomics, molecular diagnostics and liquid biopsy will be valuable for applying the latest technologies for a growing number of academic and pharmaceutical partnerships. This scientist will be primarily hands-on technically and will contribute to the strategy of Foresight’s research programs alongside team members. Your work requires excellent attention to detail, the ability to multitask, be flexible with tasks and schedules and ability to work both independently and in a team environment. This position has flexibility for fully onsite, hybrid or remote work; if hired as remote worker, quarterly travel to our headquarters in Colorado is expected.

What You Will Bring:

• MS or PhD in computational biology, bioinformatics, genomics, statistics, computer science, or related fields

• At least five years of experience developing next-generation sequencing (NGS) data pipelines, using standard NGS bioinformatics tools (e.g. samtools, bedtools, BWA, IGV), and accessing external genomic databases (e.g. TCGA, COSMIC)

• Strong data analysis and visualization skills, leveraging relevant Python or R packages (scipy, numpy, matplotlib, pandas, ggplot2, dplyr)

• Experience with algorithm development and statistics, demonstrated by a track record of applying them to relevant scientific problems

• Proficiency with Python, R, or similar programming languages, comfortable working in a Linux server-based environment, and familiar with developing code with GitHub

• Ability to work with both computational and experimental scientists in our highly collaborative environment

• Excellent oral and written communication skills for both scientific and general audiences

What You Will Do:

• Apply expert knowledge of molecular and computational biology to develop, test, and improve algorithms for detecting minimal residual disease

• Inform experimental design and provide real-time assessments of assay performance & quality control to help the R&D assay development team rapidly develop experimental methods

• Provide the analysis, interpretation, and reporting of results using cloud-based bioinformatic pipelines

• Communicate pipeline development work and results to both internal (e.g. computational and experimental teams) and external stakeholders

• Keep Foresight at the forefront of clinical diagnostics by identifying and developing new technologies

This role is offering a salary between $100,000-$140,000, generous equity, along with medical, dental and vision benefits. You will be working on interesting problems with extremely high impact. We promote the professional development of our employees and will encourage upward mobility within the company for high performing employees. Foresight Diagnostics is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.